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Blood Test At Home, Laser Light Can Cast A Shadow, 25 Starship Launches In 2025

🤖 Tech & Computer Science

To improve synthetic diamond sorting by quality, researchers developed a new dataset and modified the YOLOv8n model, creating "YOLOv8n-adamas." This model features an enhanced backbone network and an attention-based dynamic detection head, which boosts detection precision and recall. YOLOv8n-adamas demonstrated a 4% precision increase, a 2.7% recall improvement, and better mean average precision at multiple IoU thresholds compared to YOLOv8, outperforming other top models on this dataset and supporting automated quality assessment in synthetic diamond manufacturing.

Researchers found that Vision Transformers (ViTs) don't need pre-trained features for strong downstream performance. Instead, transferring only attention patterns from a pre-trained model—through "attention transfer"—lets a new model learn its own features from scratch, achieving similar accuracy. This method enables ensembling with the pre-trained model for improved results, though it may struggle with distribution shifts.

⚛️ Physics and Chemistry

Tech giants like Amazon, Microsoft, Google, and Meta are investing in next-generation geothermal energy, signaling its potential for widespread commercial success. Startups like Fervo Energy and Sage Geosystems are developing enhanced geothermal systems that create their own heat reservoirs by drilling deep into the Earth. These projects aim to power data centers with clean, reliable energy, with significant developments expected by 2027-2028. Unlike traditional geothermal, this method involves creating fractures in deep rock to extract heat, offering a promising low-carbon energy source.

Researchers at Brookhaven National Laboratory have discovered that a laser beam can cast a shadow under specific conditions, challenging conventional ideas about light. By using a ruby crystal and certain laser wavelengths, they showed that a laser could block light through a nonlinear optical process, creating a visible shadow. This finding opens new possibilities for technologies involving optical switching and precise light control, such as high-power lasers. The discovery was born from an unexpected lunch discussion about laser physics.

🧬 Biology & Medicine

SiPhox Health is developing a home-based blood test system using a silicon photonic chip, capable of measuring 20 biomarkers. This device, still in research phase and not yet FDA-cleared, aims to improve the convenience of chronic disease management by offering faster, at-home results. Founded by former MIT researchers, SiPhox’s technology miniaturizes lab-grade optical equipment onto scalable chips, making blood testing more accessible and reducing the need for inconvenient lab visits. The company also offers mail-in blood tests using approved technology.

A study found that combining a history of infections with exposure to traffic-related air pollution (TRAP) increased the risk of Alzheimer’s disease (AD) by 177% in adults aged 60-75. This supports the idea that AD is a "multi-hit" disorder, with various risk factors, including infections and TRAP, contributing to its development. Researchers suggest targeting multiple risk factors simultaneously could help prevent AD onset, though more research is needed on this approach. The study analyzed data from over 100,000 individuals from the UK Biobank.

Researchers at Washington University have linked disease-related proteins and genes in cerebrospinal fluid (CSF) to identify cellular pathways driving Alzheimer’s disease progression. This study is the first to use CSF from living patients, providing a more accurate representation of brain activity compared to postmortem brain tissue. The findings offer a more holistic view of the disease, identifying potential therapeutic targets by examining protein activity linked to genetic factors. This could help pinpoint genes responsible for Alzheimer’s and the pathways they affect.

đź”­ Space & Astronomy

SpaceX aims for 25 Starship launches in 2025, with plans to eventually reach 100 launches annually and even daily flights. This follows a successful test where the booster was caught by the Mechazilla landing tower. Although ambitious, these goals face regulatory hurdles, as SpaceX requests FAA approval to increase launch frequency. Despite challenges, CEO Elon Musk remains focused on rapid rocket reuse, stressing that more flights will accelerate learning and development.

On November 10, Ivar Sandland in Northern Norway witnessed a rocket launch against a backdrop of auroras, leaving behind clouds of trimethyl aluminum. The launch was part of a NASA experiment during a minor geomagnetic storm. Sandland, who was on a road trip, initially mistook the clouds for a strange phenomenon before learning from local news that it was a rocket launch from Andøya Space Center.

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